Intense Hydration Ingredients

OUR X TAZ MASK INCORPORATES ONLY CLINICALLY PROVEN EFFECTIVE INGREDIENTS, HERE ARE THE SCIENTIFIC FACTS:

Hyaluronic Acid

Hyaluronic acid (HA), or hyaluronan, is a major component of the extracellular matrix of connective tissue (CT) involved in tissue repair of all tissues in humans, and is crucial to the healthy functioning of our joints, eyes and other organs. Studies show that HA effectively reduces inflammation and prevents oxygen free radicals from damaging newly formed CT (skin cells) and is paramount importance in wound healing by stimulating fibroblast proliferation (production of new skin cells).(Goa & Benfield, 1994) The single most important fact for healthy skin is adequate moisture.(Fore, 2011) Hyaluronic acid can hold up to 1000 times its own weight in water, and like glycerin, moderates transepidermal water loss by attracting water from deeper layers of the dermis to keep the surface of our skin hydrated. Low-molecular weight hyaluronan is clinically proven to smooth out wrinkles and erase fine lines by adding volume via water absorption. Hyaluronic acid is necessary for maintaining the structural integrity of the extracellular matrix of dermal tissue and is scientifically proven to improve elasticity.

Allantoin

Allantoin moisturizes by softening keratin, a major component of the skin to aid in the treatment of dry by improving the skin’s moisture binding capacity. Enhances the desquamation of the superficial layer of dead skin cells, increasing the smoothness of the skin; promoting cell proliferation and wound healing; and is considered a soothing, anti-irritant skin protectant because of its neutralizing-effects against irritant and sensitizing agents. (Gottschalck et al. 2008)

CLINICALLY PROVEN

Vitamin B3 (Nicotinamide)

Niacinamide, also known as nicotinamide or vitamin B3 is an essential anti-oxidant that regulates cell metabolism and regeneration. Niacinamide is an effective anti-aging agent in concentrations at 5%. In some studies, Vitamin B3 improved skin elasticity, erythema and pigmentations after 3 months of topical application. (Ganceviciene et al. 2012) Niacinimide is able to improve skin barrier functions by increasing ceramide concentrations and other intercellular lipids levels in epidermis. In one study, applying a formulat containing niacinamide twice daily revealed that niacinamide could reduce inflammation, decrease Trans-Epidermal Water Loss (TEWL) and increase stratum corneum thickness. (Mohammed, 2013) Niacinamide was shown to significantly decrease TEWL in atopic dry skin.(Ganceviciene et al. 2012) In randomized, controlled, comparative studies of the stratum corneum integrity, moisturizers containing niacinamide yielded more rapid and sustained improvement of dryness and stratum corneum barrier than conventional moisturizers (Mohammed, 2013)

Vitamin E (Tocopherol)

Vitamins B¬3, B5, C & E are considered the most important antioxidants because their low molecular weight allows for excellent skin penetration.(Ganceviciene et al, 2012) Vitamin E has astringent properties which help to soothe and prevent inflammation while increasing the ability of the stratum corneum to retain moisture. Vitamin E accelerates epithelialization and reduces the harmful effects of ultraviolet radiation. (Ganceviciene et al, 2012) Research indicates that Vitamin E’s strong anti-oxidant properties promotes an anti-carcinogenic-like effect and if consumed as an integral part of one’s diet may reduce the risk of cancer.2 (Wada, 2012)

Vitamin B5

D-Panthenol is the stable alcoholic analog of pantothenic acid (Vitamin B5) which acts as a moisturizer by improving stratum corneum hydration, reducing Trans-Epidermal Water Loss (TEWL) , and is crucial to maintaining soft, supple and elastic skin. softness and elasticity. D-Panthenol has been shown to have an anti-inflammatory effect on experimental ultraviolet-induced erythema (allergic reaction). Beneficial effects of dexpanthenol have been observed in patients who have undergone skin transplantation or scar treatment, or therapy for burn injuries. Vitamin B5′s effectiveness in hydrating, soothing, healing and protecting skin makes it an effective ingredient in formulations to alleviate the following conditions: acne, bed sores, minor cuts, diaper rash, contact dermatitis (produced when the skin comes in contact with irritants or allergens), eczema, insect bites, scrapes and sunburn. (Ebner et al. 2002)

Glycerin

Glycerin is a humectant, a compound capable of absorbing disproportionate amounts of water. Glycerin attracts water from the deeper layers of the dermis into the epidermis (surface) and even traps water from the surrounding air when relative humidity exceeds 70% (2013 Sirikudta W, et all), all of this effectively ensures maximum hydration to the face. Glycerol also strengthens our skin by activating transglutaminase activity and increases the turnover rate of keratinocytes in the stratum corneum, making the skin feel softer and suppler while maintain hydration. (2013 Sirikudta W, et all)

REFERENCES:

1. Sirikudta W, Kulthanan K, Varothai S, Nuchkull P (2013) Moisturizers for Patients with Atopic Dermatitis: An Overview. J Allergy Ther 4:143. doi: 10.4172/2155-6121.1000143
2. Goa, K. L., & Benfield, P. (1994). Hyaluronic acid. Drugs, 47(3), 536-566.
3. Fore, MD, J. (2006). A review of skin and the effects of aging on skin structure and function. Retrieved from https://sakai.ohsu.edu/access/content/public/Gero Nursing Honors Program/Articles linked in modules/aging skin Fore 06.pdf
4. Dweck, A. (2010). Formulating natural cosmetics. (1 ed.). Carol Stream, IL: Allured Business Media.
5. Reddy, P., & Goinath, M. (2011). A review of importance of herbal drugs in cosmetics. International Journal of Advances in Pharmacy and Nanotechnology, 3(1), 121-139.
6. Ranzato, E., & Martinotti, S. (2011). Wound healing properties of jojoba liquid: an invitro study. Journal of Ethnopharmacology, 2, 443-449.
7. Gottschalck, Tara E., and John E. Bailey.( 2008) International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: Personal Care Product Council.
8. Burnett, C. L., Heldreth, PhD., B., & , (2012). Source amino acids as used in cosmetics. Cosmetic Ingredient Review, 2-5.
9. Mohammed D, Crowther JM, Matts PJ, Hadgraft J, Lane ME (2013) Influence of niacinamide containing formulations on the molecular and biophysical properties of topical nicotinamide on atopic dry skin. International Journal of Dermatology; 44, 197-202
10. Ganceviciene, R. (2013). Skin anti-aging strategies. Journal of Dermatoendocrinology, 3(1), 308-319.
11. Ebner, F, A Heller, F Rippke, and I Tausch. (2002) “Topical Use of Dexpanthenol in Skin Disorders.” American Journal of Clinical Dermatology. 6, 427-33.
12. Fox, L.; Gerber, M.; Plessis, J.; Hamman, J. Transdermal Drug Delivery Enhancement by Compounds of Natural Origin. Molecules 2011, 16(12), 10507-10540; doi:10.3390/molecules161210507. http://www.mdpi.com/1420-3049/16/12/10507.

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